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Premature (early) menopause

Certain types of cancer treatment can cause premature or early menopause.

Menopause happens when your ovaries stop making enough female hormones. This most often takes place when you are in your 50s. But some cancer treatments might make you go through menopause at a younger age.

Causes of premature menopause during cancer treatment

• Surgery: If you have your ovaries removed (oophorectomy) or have a total hysterectomy that includes removal of your ovaries, you will go into menopause that cannot be reversed.
• Radiation therapy, chemotherapy, and hormone therapy: These treatments can cause your ovaries to fail, leading to premature menopause. This menopause can be temporary; some women regain ovarian function after treatment ends. But for other women, this menopause is permanent.

Symptoms of premature menopause

Symptoms of premature menopause are the same as for natural menopause. These can include:

• Hot flashes or flushes: These can happen at any time during the day but can be especially bothersome at night. Hot flashes may be accompanied by chills, flushing (redness and warmth) on the face, anxiety, and feeling like your heart is racing. You can learn more about hot flashes and how to manage them in Hot Flashes.
• Lower sexual desire: This can happen because of lower hormone levels, stress, or poor sleep.
• Vaginal changes: Lower hormone levels can cause vaginal dryness and thinning of vaginal tissues. These changes can make vaginal sex uncomfortable and even painful.

Treatment of premature menopause

Female hormones (estrogen and/or progesterone) are sometimes used to help manage menopause symptoms. This is called menopausal hormone therapy. It comes in the form of a pill, patch, or less often, a vaginal ring.  

Some women with cancer might not be able to take these hormones.

If you have breast, endometrial, or ovarian cancer, your doctor may advise against hormone therapy. That is because hormones might promote the growth of these types of cancer. If you can’t take hormone therapy, there may be other treatments to help you manage your symptoms.

If you have questions or concerns about hormone therapy, talk with your cancer care team. If you and your team decide menopausal hormone therapy is the best treatment for you, be sure you understand what to watch for while you take it. It’s important that you have regular checkups so that your dose can be changed if needed.

Pain during vaginal sex

If you have dryness, narrowing, or other changes in your vagina, you might have pain during sex. This is called dyspareunia. You might feel pain in your vagina itself or in the tissues around it, like your bladder and rectum.

Causes of pain during vaginal sex

The most common cause of pain during sex is vaginal dryness or narrowing from cancer treatment. The walls of your vagina might also get thinner and less stretchy.

If your cancer treatment includes hormone therapy or radiation to the pelvis, or if you’ve gone through premature menopause, your body might not create enough natural lubricant or moisture to make your vagina slippery. This can cause irritation or pain during sex. You might also be more likely to get bladder infections.

If you have pelvic surgery or radiation to your pelvis, your vagina might become shorter and narrower. This can also make sex painful or awkward.

Managing pain during sex

Having sex might take some planning. These tips may help lessen your pain and make sex more enjoyable.

If you have pain in or around your genitals during sex

• Tell your health care team. Tell your cancer care team or gynecologist about the pain. Don’t let embarrassment keep you from getting medical care.

• Spend extra time on foreplay. The pain might not be as bad if you feel very aroused before you start vaginal sex. Your vagina expands to its fullest length and width only when you are highly excited. This is also when the walls of the vagina produce lubricating fluid. It may take a longer time and more touching to get fully aroused.
• Use water-based lubricating gel. This can be used in and around your vagina before vaginal penetration. You can also use lubrication suppositories (soft gel pellets) that melt during foreplay.
• Let your partner know if any types of touching cause pain. Show your partner ways to caress you or positions that don’t hurt. Usually, light touching around the clitoris and the entrance to the vagina won’t hurt, especially if the area is well-lubricated.
• Try different sexual positions. For vaginal sex, try a position that lets you control the movement. Then, if deep penetration hurts, you can make the thrusts less deep. You can also control the speed.

If you have pain in other parts of your body

• Plan ahead. Talk with your partner about when you want to have sex. This will give you some time to prepare mentally and physically.

• Take any pain medicines ahead of time. If you use medicine to manage your pain, take it an hour or so before having sex so it will be working when you’re ready.
• Try different sexual positions. Find a position that puts as little pressure as possible on the sore areas of your body. If it helps, support the sore area and limit its movement with pillows. If a certain motion is painful, choose a position that doesn’t require it or ask your partner to take over the movements during sex.
• Talk with your partner. Tell your partner what you would like and what makes you most comfortable.
• Focus on your feelings of pleasure and excitement. This might help your pain to fade into the background.

Vaginal dryness

Vaginal dryness can be caused by premature (or regular) menopause or by treatments that affect your pelvic organs. There are hormonal and non-hormonal treatments that might help you manage this dryness.

Managing vaginal dryness with lubricants

If you have dryness, vaginal lubricants can help make sex more comfortable. There are several different options, including water-based, silicone, and oil-based lubricants. Place them in and around your vagina before vaginal penetration. You can also use lubrication suppositories (soft gel pellets) that melt during foreplay.

You can find lubricants near the birth control or feminine hygiene products in pharmacies or grocery stores. Be sure to read the labels, and talk with a nurse, doctor, or pharmacist if you have questions.

• Choose a water-based or silicone gel that has no perfumes, coloring, spermicide, herbal remedies, or flavors. These additions can irritate your genital tissues.
• Petroleum jelly, skin lotions, and other oil-based lubricants are not good choices for vaginal lubrication. These products can cause yeast infections or other vaginal problems.
• If you and your partner use latex condoms, stay away from oil-based lubricants as they can damage the latex. Stick with water- or silicone-based products.
• You might want to avoid using condoms or gels that contain nonoxynol-9 (N-9). N-9 is a birth control agent that kills sperm, but it can irritate the vagina and worsen pain.

Managing dryness with vaginal moisturizers

Many women with cancer who have vaginal dryness use vaginal moisturizers several times per week. Vaginal moisturizers help keep your vagina and vulva moist and more comfortable. For the best absorption, apply these at bedtime.

Vaginal moisturizers do not replace lubricants for sexual activity because they do not make your vagina slippery enough to ease penetration. 

Managing dryness with vaginal estrogens

Vaginal estrogen therapy is sometimes used to treat vaginal dryness, narrowing, and atrophy (when the vaginal walls get thinner and less stretchy).

Vaginal hormones are applied to the genital area. They come in gel, cream, suppository, ring, and tablet forms. Most are put into the vagina, although some creams can be applied to your vulva (the outer part of your vagina).

Vaginal hormones provide small amounts of hormones to your vagina and nearby tissues. Studies show that very little of these hormones get into the bloodstream, so they should have little effect on other parts of your body.

However, if you have concerns about taking vaginal hormones, be sure to talk to your cancer care team. Ask them why they think vaginal hormones are a safe option for you. You can also ask about other treatment options that don’t include hormones.

Vaginal narrowing

Radiation to your pelvis can damage the walls of the vagina, leaving them scarred and less flexible. This can cause your vagina to get narrower and shorter. Some types of surgery can also cause changes in the length and width of your vagina.

Changes like these to your vagina can make sex and internal exams painful or even impossible. Using dilators and having pelvic physical therapy might help deal with these problems.

Managing narrowing with vaginal dilators

Vaginal dilators help keep your vagina open and more flexible after cancer treatment.  If you have had radiation or surgery to your pelvis, your doctor or cancer care team may encourage you to use dilators to prevent problems. Even if you aren’t interested in being sexually active, keeping your vagina normal in size allows more comfortable gynecologic exams.

Vaginal dilators come in various widths. You can increase the dilator size as your vagina is able to stretch more. Vibrators can also be used as vaginal dilators and may improve blood flow.

Dilators can also help you learn to relax your vaginal muscles if they are used with Kegel exercises. These exercises help teach you how to control your pelvic floor and vaginal muscles.  

Your doctor or nurse will tell you where to buy a dilator. Check with your insurance company to find out if you need a prescription.

You will also be taught when to start using it, and how and when to use it. The dilator feels much like putting in a large tampon for a few minutes. It can be used several times a week to keep your vagina from getting tight from scar tissue that may develop.

Pelvic floor physical therapy to manage vaginal pain and narrowing

Pelvic floor physical therapy teaches you how to relax your vaginal muscles so that you have less pain during sex. It is also sometimes used as part of treatment for vaginal narrowing.

If you’ve had pain during sex, you may tense the muscles inside your vagina without knowing it. This makes vaginal penetration even more painful. You might even clench your muscles so tightly that your partner cannot enter your vagina.

You can become aware of your vaginal muscles and learn to relax them during vaginal penetration. Exercises that teach control of the pelvic floor and vaginal muscles are called Kegels.

Ask your cancer care team or gynecologist to refer you to a therapist for pelvic physical therapy or pelvic rehabilitation.

Orgasm after cancer treatment

Some women report trouble having an orgasm during or after cancer treatment. There are some things you can try that might help.

• Focus on a sexual fantasy before or during sex. A fantasy can be a memory of a past experience or a daydream about something you’ve never tried. A strong sexual thought can help get you aroused and distract you from negative thoughts and fears.
• Use a hand-held vibrator for extra stimulation. Hold it yourself or ask your partner to caress your genitals with it. You can steer your partner to the areas that respond best and away from those that are tender or uncomfortable.
• If you have vaginal dryness, using a lubricant on your vulva and vagina can make touching more comfortable. If you are also using a silicone vibrator, stay away from silicone lubricants as they can damage the covering of the vibrator.
• Change the position of your legs during sexual activity. Some women reach orgasm more easily with their legs open and thigh muscles tense. Others prefer to press their thighs together.
• If you have intercourse, try different sexual positions. Positions where your clitoris gets more direct stimulation can help you reach orgasm.
• Tighten and relax your vaginal muscles in rhythm during intercourse or while your clitoris is being stroked. Or tighten and relax the muscles in time with your breathing. This helps you focus on what you’re feeling. Contract your vaginal muscles and pull them inward as you inhale and let them relax as you exhale.
• Ask your partner to gently touch your breasts and genital area at the same time or separately. Experiment with your partner to find the type of touch that most excites you.

If you continue to have trouble with orgasms, you might find sex therapy or counseling helpful. There are different techniques they can teach you. Ask your cancer care team or gynecologist for a referral.

Sexual desire (libido) after cancer and cancer treatment

Sexual desire can be affected by cancer and cancer treatment. If you are worried, depressed, nauseous (sick to your stomach), having pain, or experiencing fatigue, you may not feel like having sex. Cancer treatments that disturb the normal hormone balance in your body can also lessen your desire for sex.

Anyone going through cancer treatment might lose interest in sexual activity, at least for a time. You might not feel like it’s a priority while you are getting treated. But for most people, this is temporary.

Once you finish treatment and have recovered, your desire for sex and intimacy will most likely return. If you continue to have problems, think about seeing a therapist who has experience working with people with cancer.

Side effects that can lower your sexual desire

Some side effects of cancer and cancer treatment can lower your desire for sex while you have them.

Pain can make you feel worried, depressed, or easily discouraged. If you have these feelings, you may find it hard to get excited about sexual activity.

Other side effects from cancer and cancer treatment can also lower your desire for sex, including:

• Fatigue
• Nausea and vomiting
• Changes in how you look, such as rashes, hair loss, or an ostomy

Hormone therapy can affect desire

Cancer treatments that lower your hormone levels can reduce your desire for sex.

For example, treatment for some breast and endometrial cancers often includes? hormone therapy to lower estrogen levels because estrogen can fuel the growth of these cancers.

The goal of hormone therapy is to starve the cancer cells of female hormones. This slows the growth of the cancer.

A decreased desire for sex (libido) is the most common sexual side effect of hormone treatment.

Hormone therapy may also cause physical changes, such as:

• Vaginal dryness
• Hot flashes
• Premature menopause

Ask your cancer care team about possible side effects and how to manage them.

Emotions can affect desire and intimacy

Your emotions about cancer and treatment can also affect your interest in sex and your ability to be intimate with your partner.

You might feel:

• Afraid the cancer will come back

• Sad, frustrated, or powerless
• Bad about changes in your body
• Stressed, depressed, or anxious

Your partner might also have many of the same emotions. Talk with each other about your feelings and concerns, including how they might affect your sexual desire and response. Keeping these feelings to yourself can get in the way of being intimate, both physically and emotionally.

If your emotions about cancer and cancer treatment are making it hard for you to be intimate, talk to your cancer care team or gynecologist. They will have resources to help you, or they can refer you to a counselor or sex therapist.

Specific cancers and treatments that can affect sexual desire

Any type of cancer or cancer treatment can affect your desire for sex, at least temporarily. But some cancers and treatments are more likely to cause significant or long-term changes to the way you experience sex and intimacy.